Vol. 5 (2021): International Journal of Case Reports
Case Reports

Paget´s disease of bone in a patient on peritoneal dialysis

Flores-Padilla Guillermo1,2, Solis Jose Gabriel1,3*, Zavala-Jonguitud Luis Fernando1,4, Juarez-Villa Daniel1,5, Olascoaga-Lugo Arturo1,6
1Department of Internal Medicine, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social. México City, México. Adress: Avenida Cuauhtémoc # 330 Colonia Doctores. Alcaldía Cuauhtémoc. Ciudad de México 06725. México. 2ORCID ID: https://orcid.org/0000-0003-0697-620X 3ORCID ID: https://orcid.org/0000-0003-3532-6062 4ORCID ID: https://orcid.org/0000-0002-6405-7810 5ORCID ID: https://orcid.org/0000-0002-6462-8935 6ORCID ID: https://orcid.org/0000-0002-6557-7180


  • Paget disease of bone; kidney failure; peritoneal dialysis; denosumab

How to Cite

Flores-Padilla Guillermo1,2, Solis Jose Gabriel1,3*, Zavala-Jonguitud Luis Fernando1,4, Juarez-Villa Daniel1,5, Olascoaga-Lugo Arturo1,6. (2021). Paget´s disease of bone in a patient on peritoneal dialysis. International Journal of Case Reports, 5, 196. https://doi.org/10.28933/ijcr-2021-01-2205


Paget´s disease of bone is a disorder characterized by disorganized bone remodeling. It´s occurrence in patients with end-stage kidney disease on renal replacement therapy is rare. Here we report a case of Paget´s disease of bone in an 80-year-old male on peritoneal dialysis that presented a high level of alkaline-phosphatase with a mildly elevated parathyroid hormone level and typical imaging findings localized to the pelvis. This is the fourth reported case of Paget´s disease in a patient on peritoneal dialysis and the first treated with denosumab.


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