Vol. 3 No. 1 (2020): Open Journal of Gastroenterology and Hepatology
Research Articles

Usefulness of Castor Oil and Elobixibat and Lactulose for Bowel Preparation for Colon Capsule Endoscopy in the patients on Dialysis -Including examination of small intestinal lesions-

Naoki Hotta
Department of Internal Medicine, Division of Gastroenterology, Masuko Memorial Hospital, Aichi, Japan.
Keywords
  • Castor Oil ,Elobixibat ,Colon Capsule Endoscopy ,Patients on Dialysis
How to Cite
Hotta, N. (2020). Usefulness of Castor Oil and Elobixibat and Lactulose for Bowel Preparation for Colon Capsule Endoscopy in the patients on Dialysis -Including examination of small intestinal lesions-. Open Journal of Gastroenterology and Hepatology, 3(1), 30. https://doi.org/10.28933/ojgh-2019-12-2706

Abstract

Colon capsule endoscopy was approved for reimbursement under the national health insurance system of Japan in 2014.
Dialysis patients are potentially susceptible to bleeding because of the fragile intestine, impaired platelet function, or oral administration of nonsteroidal antiinflammatory drugs (NSAIDs) or anticoagulants. However, the capsule excretion rate after recommended bowel preparation reportedly ranges from 70% to 90%, and administration of boosters is also necessary. For dialysis patients, liquid loading is a problem. The patient on dialysis has moisture restrictions. The caster oil-based booster had an emission rate of 97%, but required a total water content of 3L. A study was conducted on dialysis patients using a protocol in which castor oil was supplemented with Elobixibat and Lactulose to determine whether booster volume could be reduced and elimination rates improved.

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